Табиғи қосылыстар негізіндегі иммуномодуляторлық қасиетке ие жаңа кешенді жемдік қоспа

Abstract

Background and Aim. Natural feed additives stimulating natural resistance of animals will allow us to obtain ecologically clean meat and dairy products. The purpose of this study is to evaluate physiological and biochemical efficiency of new complex feed additives and its experimental study. Materials and Methods. The studies were conducted on white laboratory rats of Spraque Dawley line, divided into 3 groups - control group and 2 experimental groups of animals taking feed additives. For comparison our previous feed additive was taken. The new additive includes bentonite and chlorella in addition to KI and selenium - they were formed by our new technology. In the study for 21 days, we studied blood-lymph circulation, cellular and biochemical composition of blood and lymph, humoral immunity and state of oxidative activity of blood. Feeding with feed additive increased content of protein in the diet.

Results. The use of a new complex feed additive had a positive effect on the cardiovascular and lymphatic systems, affected protein, carbohydrate and fat metabolism in the body, and promoted weight gain in animals. Taking the feed additive led to increased enzymatic activity and an increase in the content of protein, glucose, and lipids in the blood. The new feed additive has a good adsorption and antioxidant effect, reducing toxic phenomena in the body, participating in the inactivation of free radicals, exerting a protective effect on cell membranes, and increased energy expenditure with an increase in muscle mass.

Conclusion. The feed additive physiologically increased leukocytes, lymphocytes, and immunoglobulins in the blood and lymph. The new additive is high-calorie, has an antioxidant and adaptogenic effect, maintains a balance of biochemical and oxidative processes, and most importantly, has immunomodulatory properties - it enhances humoral and cellular immunity and can be recommended as a safe and effective supplement to the daily diet of farm animals.