CONTROL OF THE BIOLOGICAL ACTIVITY OF THE EQUINE INFECTIOUS ANEMIA VIRUS DURING STATIONERY AND SUSPENSION CULTIVATION

Abstract

The lack of effective vaccines to prevent the spread of infectious anemia in horses forces the use of methods based on early diagnosis, isolation and culling of infected animals. Therefore, the development of a highly sensitive and specific test system made from circulating strains of EIA virus is one of the main aspects of diagnostic value. To this end, monitoring the biological activity of the EIA virus will allow to determine the properties of the virus during stationary and suspension cultivation in a bioreactor, and to outline further ways to intensify mass production with increased economic efficiency while minimizing costs. The conclusions of the research work allow us to determine the most effective method of virus cultivation, determine its biological activity for the production of a test system, and also in the future will allow the production of a drug with standard properties.